I have a cross bike that I use for road touring and bikepacking. Of those two bikes listed, I think you would have the most fun touring on the Cannondale because it has a triple crank. In order to get the gearing needed to get up hills with a light, light touring load I had to swap out my rear derailuer for an XT mtn bike derailuer so I could run an 11-36 rear cassette. I live in the mountains of California, so some extra gears were needed to get up hills with my light touring kit. I use a seatpack, frame bag, and handlebar sling from Revelate. I know South Carolina has some hills, so think about your gearing. The other factor in bike selection for touring will be tires. I would be surprised if either of those bikes take tires wider than 28c, which may or may not be wide enough for your weight and touring kit. When I tour, I use 40c tires, which barely fit in my frame. You can tour on any bike really with bikepacking gear as none of it needs rack braze ons to mount the load, but the two factors I would weigh most highly are tire size the frame will accept and gearing. Good luck.