If it deep enough cold to remain well below freezing, the integration of VB clothing would prevent the possibility of down getting wet. The only possible way for it to get wet if if you spilled your drinking or cooking water on it.
That being said, synthetic isn't oblivious to moisture. If it gets wet enough, it will lose enough of its ability to retain heat to kill you as well. That being the case, what I pack for a winter mountaineering trip versus a winter backpacking trip differ quite a bit. High elevation, extreme cold and no trees means white gas stoves, a tent and enough insulation to reduce my chances of dieing.
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