My last trip was a 5 day 60 miler, fall trip in the smokies, and my pack with food and water(I only carried a days worth at a time) was 26 lbs.
That was with a heavier pack, a full sleeping bag for a TQ, and an extra pair of clothes. Next time I hope to get closer to the 22 lb range. I was using a 3/4 down UQ and next time I will be sporting a full length. So it may end up being 23 lbs ish.