Where are you going in the state?
That'll help immensely: "I'm going to FL," is a similar statement to "I'm going to Great Britain." (The difference in land area is only ~23,000 square miles, or about a quarter of Great Britain's or a third of FL's land area.) It takes ~9 hours to drive from the GA border to Key West down the east coast of FL on the highway, and ~2.5 hours to drive from the east to west coasts at the widest portion of the state on the highway--all of this assuming no traffic, of course.
So, before we make recommendations, where are you likely to be within an hour's drive of?