I am and Hennessy AND ENO guy. I have an ENO DN and SN and a Hennessy Deep Jungle (side zip) and Safari (bottom classic entry). I also have the ENO bugnet, but have never set it up.
I'm most comfortable in the ENO DN, with the Safari probably a close second. That being said, the Deep Jungle is great in winter with the double bottom and a pad inside.
Because I'm not an ultralite backpacker, I almost always take one of each. Last summer I camped on the Jacks River trail and I took the SN for day lounging around and the Safari (very few mosquitos) for sleeping at night. I car camped last weekend with the DN and the Deep Jungle.
If you only want one system, the ENO DN with a bugnet and tarp would be your most versatile setup. The Deep Jungle would probably be 2nd, but its pricey.